A mini review on analytical and bioanlytical techniques in study of drugs-protein interaction Singh Alka1, Gupta Bhaskar Kumar1,*, Upmanyu Neeraj1,2 1School of Pharmacy and Research, People's University, Bhanpur, 462 037, Bhopal, M.P, India 2Sanjeev Agrawal Global Educational University, Katara hills Extension, Bhopal, M.P, India *Corresponding Author E-mail: singhalka7160@gmail.com
Online Published on 31 August, 2024. Abstract The choice of a suitable analytical technique for the identification of a drug or a combination of drug mainly depends on the sample matrix complexity and the analyte concentration. The appropriate choice of an analytical method is based on properties of studied analyte such as intrinsic structure and physicochemical properties etc. The extensive development of the pharmaceutical field requires more meticulous analytical methods for the control of various diseases by means of drugs. The aim of this review article was to study the drug protein interaction with respect to various analytical methods which are applied in research and innovative field of Pharmacy. The crucial factor involved and affects the binding of drugs with Body protein is distribution as well as bioactivity of drugs in the body. In biological science and medicine, the quantitative analysis of protein in biological liquids is of great importance. The aim of the review was therefore to summarize all available examples and information about the use of current analytical applications on various categories of drugs in their dosage forms and in biological samples. The different pharmaceutical active compounds, which have been determined using different methods, are summarized for the future reference of researcher. Top Keywords Protein binding techniques, Analytical tool, Human serum albumin, Plasma protein binding, Bioanalytical studies. Top |