A Comparative study of efficacy of injectable Dexamethasone sodium phosphate versus placebo in bilateral mandibular third molar surgery Gill Supreet1,*, Kaur Yashmeet2, Kaur Tejinder3 1MDS, Consultant Oral and Maxillofacial surgeon, Amritsar 2MDS, Reader, Department of Oral and Maxillofacial surgery, Sri Guru Ram Das institute of Dental Sciences and research, Amritsar 3MDS, Professor and Head, Department of Oral and Maxillofacial surgery, Sri Guru Ram Das institute of Dental Sciences and research, Amritsar *Corresponding Author: Dr. Supreet Gill, MDS, Consultant Oral and Maxillofacial surgeon, Amritsar, Email: supreetgill20@yahoo.com
Online published on 22 August, 2019. Abstract The surgical removal of impacted third molars is one of the most commonly performed dentoalveolar surgical procedure in oral and maxillofacial surgery. Postoperatively, the most frequently encountered sequelae of surgical extraction of impacted third molars are pain, swelling and trismus. Many anti-inflammatory drugs have been used to reduce postoperative discomfort following surgical removal of third molars. The present study was undertaken in 20 patients having bilaterally symmetrical impacted mandibular third molars to evaluate the effect of dexamethasone on postoperative sequelae. The patients were randomized to receive injection dexamethasone sodium phosphate 8 mg into the deltoid muscle one hour preoperatively either in the first or second surgical extraction. In the control group 2 ml normal saline was used. Clinical examination to assess the postoperative sequelae of pain, swelling and trismus was carried out immediate postoperatively and on postoperative day 2 and day 7. The data was statistically analyzed. The results of the present study revealed that in the absence of contraindications to corticosteroid use, one hour preoperative administration of 8 mg dexamethasone in the deltoid muscle produces significant reduction in the postoperative pain, swelling and trismus. Top Keywords Extraction, Surgical Removal, Third Molar. Top |