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Indian Journal of Forensic Medicine & Toxicology
Year : 2019, Volume : 13, Issue : 4
First page : ( 547) Last page : ( 552)
Print ISSN : 0973-9122. Online ISSN : 0973-9130.
Article DOI : 10.5958/0973-9130.2019.00347.5

Study the Effects of Helicobacter Pylori Bacterial Infection on Some Liver Enzymes and Lipid Profile in Kirkuk Patients

Karomi Asma Sumiea Afram

Department of Biology, College of Science, University of Kirkuk, Kirkuk, Iraq

Online published on 27 November, 2019.

Abstract

Background

In recent years, researchers become interested in studying the relationship between the infection of Helicobacter pylori, which affects the digestive system and causes serious diseases and the prevalence of infection.

Aims

This study aims to determine the relationship between infection with this bacterium and its effects on some of the liver enzymes and lipid profile.

Material and Method

In this study, 50 samples were collected from the patients who visited Azadi Teaching Hospital and some national laboratories in Kirkuk city during the period of May 2018 to November 2018. After the tests were carried out, 25 infected samples were found, and 20 non-infected samples were considered control and completed; whereas 5 samples were for the delay. 45 samples were tested for diagnosing: 1) Helicobacter pylori (H. pylori); 2) The Serum Glutamic Oxaloacetic Transaminase (SGOT); 3) Serum Glutamic Pyruvic Transaminase (SGPT); and 4) Triglycerides (TG) and Cholesterol. The statistical software package was used to analyze the results of this work.

Results

This study found no significant differences between biliary disease and age and gender, but there was a relationship between biliary disease and age group (11–30). There was also a relationship between H.p infection disease and gender. The prevalence of infection among females was found to be higher than that of males. The effects of H.p infection on certain enzymes were also found to be non-significant, such as SGOT, SGPT, TG and cholesterol at (p <0.05). However, there was a decrease in the cholesterol level between the group of patients and the control group.

Conclusion

H. pylori infection is not directly related to gender or age as it can affect both males and females of all ages. It has indirect effects on liver function by affecting some liver enzymes and may change the levels of cholesterol and triglycerides.

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Keywords

H. pylori, Liver function, lipid profile.

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