Misuse of Pain Killer Drugs (Diclofenac Na) for in Patients with Hyperuricaemia and Other Risk Factors in Al-Najaf Province Assi Mohammed Abdulrazzaq1,*, Raheem Saad Saleem1 1Department of Community Health, College of Health and Medical Techniques, Al-Furat Al-Awsat Technical University, Iraq *Corresponding author: Mohammed Abdulrazzaq Assi. E-mail: razaq_assi@yahoo.com.
Online published on 27 November, 2019. Abstract Background Non-Steroidal Anti-Inflammatory Drugs or pain killer drugs have the effect of increasing the levels of plasma uric acid that leads to renal problems as a one of their adverse effects and also associated with a fairly high incidence of renal adverse drug reactions. Uric acid is a byproduct of purine metabolism produced in blood from endogenous purine substances or from the diet. The aim of current study was to study the correlation between the use of pain killer drug and elevation of serum uric acid in patients suffering from pain of a variety of diseases. Methods This study was executed on patients of different ages suffering from pain, attended main hospitals in Al-Najaf province. Results The results showed that all risk factors and different diseases had closely the same effects and regarding the range of relationships for using pain killer drugs and increasing uric acid in outpatients suffered from different diseases. The effects of varying ages in these results had obviously appeared through the numbers of patients. The gender (male and female) had different rates about the numbers that they were suffering from different diseases and hyperuricaemia. These results showed significant differences (p<0.05) in patients used pain killers with different dosages, but with lowest rates of uric acid in their blood. Conclusions Pain killers are used in patients suffered from different diseases and the hyperuricaemia cases appeared in patients that they were having different diseases. However, there are different effects of different risk factors and diseases noticed between the two genders. Also, there were differences between employed and non-employed patients in case of hyper and hypouricaemia. Top Keywords Non-Steroidal Anti-Inflammatory Drugs, pain killer, diclofenac Na, renal disease, uric acid, hyperuricaemia, UTI. Top |