(3.238.87.31)
Users online: 12147     
Ijournet
Email id
 

Indian Journal of Forensic Medicine & Toxicology
Year : 2019, Volume : 13, Issue : 4
First page : ( 1085) Last page : ( 1089)
Print ISSN : 0973-9122. Online ISSN : 0973-9130.
Article DOI : 10.5958/0973-9130.2019.00444.4

Teratocarcinoma-Derived Growth Factor-1 (TDGF-1): A Guide Molecule for Monitoring the Treatment Success of Iraqi Patients with Colorectal Carcinoma

Al-Fahdawi Abdul-Rahman M. Geeran1, Hamad Mohammed A.2,*, Al-Hadithy Eman M. Rasheed3

1Department of Human Anatomy, College of Medicine, University of Anbar, Al-Anbar, 31002, Iraq

2Department of Biotechnology, College of Applied science, University of Fallujah, Al-Anbar, 31002, Iraq

3Department of Physiology, College of Medicine, University of Fallujah, Al-Anbar, 31002, Iraq

*Corresponding author: Mohammed A. Hamad, dr-moh75mnr@uofallujah.edu.iq; 009647818630925 Poster address: (Zip: 00964, University of Fallujah) Education Hospital; Fallujah, Anbar, Iraq

Online published on 27 November, 2019.

Abstract

This study was carried out in Al Ramadi Teaching hospital from the period March 2013 till August 2013 on sixty two (62) Iraqi patients with colorectal carcinoma. Their ages range from 8–47 years old complain from disturbances in GIT. All patients were visiting the department of surgery in Al-Ramadi teaching hospital. Five ml venous blood was withdrawn from the patients and placed into a plain test tube without anticoagulant to obtain sera. The blood samples were taken from the patients before and after receiving adjuvant chemotherapy and from the healthy individuals (control group 2). The results obtained regarding estimation of TDGF-1 levels in colorectal carcinoma patients revealed that there is a higher significant difference in their concentrations before treatment (3.0 ng/ml) and after chemotherapy treatment (1.2 ng/ml). TDGF-1 level in control group 2 was (0.1 ng/ml). that means, the expression of this TDGF-1 marker in cancerous patients was higher compared with low in normal tissues make it is the target of chemotherapy so evaluation of this marker during receiving chemotherapy give an effective results to choose the best mode of treatment and exclude the non effective ones.

Top

Keywords

colorectal carcinoma, TDGF-1.

Top

  
║ Site map ║ Privacy Policy ║ Copyright ║ Terms & Conditions ║ Page Rank Tool
733,298,736 visitor(s) since 30th May, 2005.
All rights reserved. Site designed and maintained by DIVA ENTERPRISES PVT. LTD..
Note: Please use Internet Explorer (6.0 or above). Some functionalities may not work in other browsers.