Oxidative and Antioxidant Status in both Serum and Saliva of Patients with Idiopathic Facial Weakness (Bell's palsy) Alyassiri Ali Mihsen Hussein1,*, Zaidan Taghreed Fadil1 1Department of Oral Diagnosis, College of Dentistry, University of Baghdad, Baghdad City, Iraq *Corresponding author: Ali Mihsen Hussein Alyassiri, Department of oral diagnosis, College of Dentistry, University of Baghdad, Baghdad city, Iraq
Online published on 27 November, 2019. Abstract Oxidative stress is a status related to over production of reactive oxygen species forming through various oxidation pathways and a disruption of the oxidant-antioxidant balance due to a decrease in total antioxidant capacity. One-hundred and twenty (120) subjects were participated in this study; they were divided into two groups: Group one: Eighty (80) Bell's palsy patients included in this study. Diagnosis of patients with Bell's palsy based on House-Brachmann Scale (HBS, 1996); this diagnosis and group two: Forty (40) healthy control subjects (volunteers) with no signs and symptoms of any systemic diseases, with matched ages and genders with BP patients. The results of this study showed a highly significant reduction in both serum and salivary MDA, also the results of vitamin E showed highly significant increase in both serum and salivary vitamin E mean after treatment. Regarding the TAO in this study showed significantly increased TAO after LLLT. Oxidative stress is elevated in biological samples of patients with Bell's palsy and may help to clarify the etiopathogenesis of the disease. Top Keywords Facial paralysis, Superoxide dismutase, Glutathione. Top |