Assessment of Melatonin and Oxidant-Antioxidant Markers in Infertile Men in Thi-Qar Province Washeel Khalid G.1, Sarhat Entedhar R.2, Jabir Talal H.3 1Biology Dept, College of Science, University of Thi-Qar 2Department of Basic science, Dentistry College, Tikrit University 3Thi-Qar Health Directorate Online published on 27 November, 2019. Abstract The present study aimed to investigate the level of melatonin MDA, GSH in infertile men compare with the fertile men in Al-Hussein hospital in Thi-Qar province, Iraq, from 10th of January 2019 to 10th of March 2019. The study included 65 infertile men whose age were between 21–40 years, also included 35 healthy individuals with same age who visited blood bank in Thi-Qar province for blood donation. Five ml of blood sample was collected subject enrolled from each one for measurement of serum albumin, reduced glutathione (GSH), malondialdehyde (MDA) by spectrophotometric kit. as well as estimation of melatonin by ELISA technique. The study showed that melatonin was reduced significantly in infertile men (226.5±11.9 pg/ml) as compared with healthy control (381.6±12.8 pg/ml). Also there was significant increase in the level of MDA in infertile men (4.15±2.34 pg/ml) as compared with healthy control (1.71±0.44 pg/ml). The study showed that the lowest mean level of glutathione was recorded in infertile mean (31.8±2.5 mmol/l) as compared with healthy control (63.7±2.1 mmol/l) with a significant relation (p<0.05). The study showed that the minimum level of albumin was recorded in infertile mean (4.24±0.29 g/dl) as compared with healthy control with highly significant relation. Top Keywords Melatonin, MDA, Glutathione, Male infertility. Top |