Testicular Feminization Syndrome: A Case Study Reddy M. Rupa*, Reddy M.V. Naveen Associate Professor, Shadan Institute of Medical Sciences, Hyderabad, Telangana, India *Corresponding author email: rupaobg@yahoo.co.in
Online published on 11 November, 2014. Abstract We report a rare case of testicular feminization syndrome in a 24 years old patient. This is a syndrome due to androgen insensitivity. The patient is phenotypically female with male Karyotype (46XY). The patient is completely feminine with well-developed breasts, female external genitalia, blind vagina, absent mullerian structures, undescended testes and sparse axillary and pubic hair. The gonad (undescended testes) may be intra-abdominal, inguinal or labial. The patient was surgically treated with bilateral orchidectomy and vaginal reconstruction. The incidence of testicular feminization syndrome is reported to range from 1 in 2,000 to 1 in 62,400. Top Keywords Cryptorchidism, Androgen insensitivity syndrome, Orchidectomy, Malignant transformation, X linked recessive. Top |