Acute toxicity and teratogenic impacts of construction waste runoff on zebrafish embryo Rajasegaran T1, Jeevanaraj P1, Rusdi NA1, Yu K X1, Hashim Z2, Kue CS1,* 1Department of Diagnostic and Allied Health Sciences, Faculty of Health and Life Sciences, Management & Science University, 40100, Shah Alam, Selangor, Malaysia 2Department of Environmental Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia *Corresponding Author: Dr. Kue Chin Siang Senior Lecturer Faculty of Health and Life Sciences, Management & Science University, 40100, Shah Alam, Selangor, Malaysia Email: cskue@msu.edu.mv; cskue3632@gmail.com
Online published on 5 October, 2018. Abstract Construction waste is on rise in developing country; heavy metals in construction waste may harm environment and residents. The aim of this research was to study the toxicity and teratogenicity of construction waste runoff by using zebrqfish embryo. The heavy metal analysis shows that the concentrations of Hg, As, Cd, Cr, Cu, Ni and Pb have exceeded the Malaysian Water Quality Standard. At 100% runoff, 92% and 74% of the zebrqfish embryo showed curve trunk and head malformation respectively, and yolk sac edema (19.8±6.1%) and pericardial edema (61.5±0.86%). This suggest that construction waste runoff was contaminated with heavy metals and teratogenic. Top Keywords Construction waste, runoff, heavy metals, zebrqfish embryo, teratogenicity, toxicity. Top |