Incidence and Profile of Gross Congenital Malformations in a Tertiary Care Hospital in North India Dalal Jagjit Singh1, Kapoor Rohit2, Jhajra Sandeep3, Gupta Manish4 1Associate Professor, Department of Neonatology, Pt. B. D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana 2Junior Resident, Department of Neonatology, Pt. B. D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana 3Assistant Professor, Department of Neonatology, Pt. B. D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana 4Senior Resident, Department of Neonatology, Pt. B. D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana *Corresponding Author: Dr. Manish Gupta, Senior Resident, Department of Neonatology, Pt. B.D. Sharma PGIMS, Rohtak, Haryana, e-mail: manishgupta.89@gmail.com
Online published on 23 December, 2019. Abstract Background With better management of nutritional deficiency and infectious diseases, congenital malformations are becoming important cause of perinatal and infant mortality and morbidity in developing world. Due to lack of National Birth Defect surveillance the true magnitude of births affected by congenital anomalies in India is unknown. Need for data regarding congenital malformations arises so as to get the burden and to assess their impact on health and rehabilitation services in a developing country like India. Objectives To determine the incidence and profile of congenital malformations among live births at a tertiary care hospital in North India. Method A prospective analysis was carried from November 2016 to October 2018. All live borns during study period were included. Diagnosis of congenital malformations was based on clinical examination of newborn. Other investigations like Xray, ultrasonography of skull and abdomen and two dimensional echocardiography were done where required to rule out other associated anomalies. Results During the study period, there were 22, 460 live births. Among them, 265 had congenital malformations resulting in an incidence of 11.8 per 1000 live births. Out of these, 245 babies had single and 20 babies had multiple congenital malformations. Out of these, 54.71% babies were males and 30.9% were preterm. Most of the mothers were multiparous (75%) and in the age group of 20–30 years (81.3%). The most common system involved was central Nervous system (20.75%) followed by cardiovascular system (17.35%) and gastrointestinal system (15.84%). Meningomyelocele (10.5%) was the commonest anomaly in central nervous system. Conclusions The incidence of congenital malformations in our study was found to be 11.8 per 1000 live births. The most common system involved was central nervous system Top Keywords Gross Congenital Malformations, Incidence, tertiary care hospital, Neonate. Top |