Changes in the Brainstem Auditory Evoked Potentials in the Chronic Obstructive Pulmonary Disease Kamra Monika1, Walia Lily2,*, Kochhar Sonia3 1Scholar, Department of Physiology, Maharishi Markandeshwar Institute of Medical sciences and Research, Maharishi Markandeshwar University, Mullana, Ambala 2Proffesor and Head, Department of Physiology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Maharishi Markandeshwar University, Mullana, Ambala 3Associate Prof, Department of Physiology, AIIMS, Bathinda *Corresponding Author: Dr. Lily Walia, Prof & Head, Department of Physiology, Maharishi Markandeshwar Institute of Medical, Sciences and Research, Mullana, Ambala.(Haryana), e-mail: dr.lilywalia@gmail.com
Online published on 23 December, 2019. Abstract Chronic obstructive pulmonary disease is characterized by progressive and irreversible pulmonary airway obstruction. Brainstem auditory evoked potentials (BAEPs) are the voltage changes generated in the brain. BAEPs are recorded from the ear and vertex after application of auditory click stimuli to the auditory pathway. Aims and objectives To find out the changes in the Brainstem Auditory Evoked Potential values in the Chronic obstructive pulmonary disorder (COPD) patients and to know the effect of severity of COPD on the same. Materials and Method The study was conducted in the department of Physiology, Maharishi Markandeshwar Institute of Medical sciences and research, Mullana (Ambala). There are total number of 150 subjects in our study in between the age group of 35-65yr. There are two groups: 1. Control group 2. Study group. Each group consists of 75 subjects containing both males and females. Result and analysis There was no significant difference in the age in control and study group. PFT parameters showed highly significant changes in the COPD as compared to control group. Wave-V shows significant prolongation in left ear (p-value 0.04) and highly significant prolongation in right ear (p-value 0.006) in COPD patients. Interpeak latency I-III of right ear showed significant prolongation (p-value 0.01) in COPD patients. I-V interpeak latency of left and right ear showed highly significant prolongation (p-value less than.001) and amplitude of wave I-Ia also showed significant reduction in COPD group (p-value 0.04). There is significant delay in latency of wave-I of left side (p-value 0.03) with increasing degree of severity of COPD. None of the other absolute wave latencies and interpeak latencies show any significant change with degree of severity of the disease. Conclusion In our study, there are significant changes are seen in the BAEP values in COPD patients. These significant results may be due to excessive smoking induced hypoxia which inturn affects the auditory mechanism and hence BAEP values. Top Keywords COPD, BAEP, PFT, Wave-V, p-value. Top |