Topical Approach Versus Systemic Antimicrobial Therapy for Treating Diabetic Foot Infection in Ninevah Alabdaly Moayad1, Hassan Taha2, Bayati Shahbaa Al3 1Lecturer, PhD, Department of Family and Community Medicine, Medical College, University of Ninevah 2Assistant Professor, Department of Surgery, Medical College, University of Ninevah 3Lecturer, Department of pharmaceutical Medicine, Medical College, University of Ninevah Online published on 23 December, 2019. Abstract Infection may be a common character of advanced diabetic foot unwellness and therefore the commonest reason for diabetes-related hospitalizations and lower extremity amputations. The topical (local) treatment has the benefits of avoiding systemic adverse effects, providing an enhanced target area concentration, and permitting the utilization of agents not offered for systemic treatment. The aim of this study is to show the effect of topical antimicrobial approach versus systemic antimicrobial therapy for treating diabetic foot infection in Ninevah. We included randomized controlled trial that allocated people individually as a two-group patient, parallel (topical and systemic) studies involving patients with an infected diabetic foot. The results were expressed in a reduction in risk (efficacy) 91% and the relative risk 0.09 with 95% confidence intervals (0.011–0.696). The results suggest that topical infiltration treatment, when accompanied by appropriate wound care, can provide a therapeutic alternative to a broad-spectrum systemic antibiotic agent. Top Keywords Diabetic foot infection, efficacy, relative risk. Top |