A 4-Day Plaque-Regrowth Anti-Plaque Effect of a Combination of Green Tea and Salvadora Persica L.: A Randomized Controlled Crossover Clinical Trial Salah Rasha1, Mohammed AN1, Abdulbaqi Hayder Raad1,* 1Department of Periodontics, College of Dentistry, University of Baghdad, P.O. Box 1417, Baghdad, Iraq *Corresponding Author: Hayder Raad Abdulbaqi, Department of Periodontics, College of Dentistry, University of Baghdad, P.O. Box 1417, Baghdad, Iraq, Phone: +964-7733604332, Email: hayderraad@codental.uobaghdad.edu.iq
Online published on 23 December, 2019. Abstract Background In earlier studies, a combination of 0.25mg/ml green tea and 7.82mg/ml Salvadora persica L. aqueous extracts (Co) had been found to exhibit anti-bacterial and anti-adherence effects against primary plaque colonizers biofilm in vitro and antiplaque effect as a mouthwash for a period of 24h in vivo. The aim of current study was to evaluate anti-plaque efficacy of Co mouthwash for a longer period of 4 days in vivo. Method A 4-day plaque re-growth double-blinded randomized crossover trial was carried out. A week after receiving polishing and scaling, all participants (n=14) received polishing at base line and rinsed with 15ml of randomly allocated mouthwashes (either Co, 0.12% chlorhexidine or placebo) twice daily without oral hygiene measures for 4 days. After 24h and 4 days’ time points, plaque index was recorded, and then the participants entered a 6-day washout period with regular oral hygiene measures. The same protocol was repeated for the next 2 mouthwashes. Results The Co mouthwash significantly reduced plaque accumulation as compared to Placebo and chlorhexidine). Conclusion The Co mouthwash has antiplaque activity for a 4-day period and might be a potential alternative to synthetic mouthwashes. Top Keywords Salvadora, green tea, dental plaque, mouthwash, chlorhexidine. Top |