The Anti Inflammatory Effect of Pumpkin Seeds Oil in Treatment of Gingivitis; Clinical Study Othman Ahmed Adel1, Saleh Muntaha Fawzi2,*, Saleh Taif Mahdi3 1College of Dentistry, Oral Diagnosis Department Uruk University, Iraq 2College of Dentistry, Oral Diagnosos Department AL-Mustansiriyah University, Iraq 3College of Dentistry, Periodontic Department, Uruk University, Iraq *Corresponding Author: Muntaha Fawzi Saleh, College of Dentistry, Oral Diagnosos Department, AL-Mustansiriyah University, Iraq, Email: dr.muntahafawzi@yahoo.com
Online published on 23 December, 2019. Abstract Background Many studies had focused on investigating the anti inflammatory roles of herbal medicines such as oils rich in fatty acids. Pumpkin seeds oil contains omega-3, omega-6 fatty acids and other fatty acids (oleic, linoleic and palmitic acids). Six phenolic acids (protocatechuic, caffeic, syringic, vanillic, p-coumaric and ferulic) were detected. Pumpkin seeds oil is a good source of vitamins, minerals and antioxidants. Many people have difficulty in controlling plaque build-up and preventing gingivitis using only conventional teeth cleaning. The objective of this study was to determine the anti inflammatory properties of pumpkin seeds oil for treatment of gingivitis. Method In this study 58 healthy male patients were involved their age ranged was (20–30) years. They were diagnosed having gingivitis according to the criteria of Loe and Sillness gingival index. These 85 patients were equally divided into two 29-subject groups as study and control groups. The patients in the study group were instructed to brush their teeth twice daily morning and before the bed time and then apply few drops from the pumpkin seeds oil on the brush and make a gentle massage for one minute to the gingiva. Patients in control group were instructed to do the same protocol but using normal saline (placebo without any active ingredient) instead of the pumpkin seeds oil. All the patients were examined again after one week to evaluate the cases prognosis. Results Data from current study showed the index of gingivitis for selected teeth before treatment. The highest score was for the maxillary right first molar (2.7), while the lowest score was for the mandibular right first bicuspid (1.8). Conclusion This study proved that pumpkin seeds oil is a potent anti inflammatory agent that can be used topically for treatment of gingivitis without any side effects. Top Keywords Pumpkin seeds oil, gingivitis, anti-inflammatory properties, Omega-3. Top |