Indian Journal of Public Health Research & Development
Year : 2019, Volume : 10, Issue : 10
First page : ( 2304) Last page : ( 2307)
Print ISSN : 0976-0245. Online ISSN : 0976-5506.
Article DOI : 10.5958/0976-5506.2019.03200.5

Simulation of the Warfarin Drug-Binding Nano-Metal Induction for Serum Albumin

Hamad Hasan Tuhmaz¹

¹College of Medicine, Thi-Qar University, Iraq

Online published on 23 December, 2019.

Abstract

Metallic bio-conjugated nanoparticles are known to be a common example for these characteristics, out of which gold NPs (AuNPs) in particular are heavily exploited due to their inert nature and high electron density. Coating the AuNPs with albumin proteins is useful due to their biocompatibility and their ability to bind many drug molecules. Among carrier proteins, human serum albumin (HSA) is considered one of the major transporter proteins in the blood plasma. It constitutes approximately half of the protein found in human blood. Curve fitting method allow you to create, access, and modify curve fitting objects. It also allows, through method like plot and integrate, to perform operations that uniformly process the entirety of information encapsulated in a curve fitting object. The results are appeared that describe the variation of the NPs concentration with time, the fluoresce spectrum with nanoparticles. The analytical data are corresponding with experimental information.

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Keywords

Drug-binding, Simulation, serum albumin.

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