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Indian Journal of Public Health Research & Development
Year : 2019, Volume : 10, Issue : 8
First page : ( 1194) Last page : ( 1199)
Print ISSN : 0976-0245. Online ISSN : 0976-5506.
Article DOI : 10.5958/0976-5506.2019.02058.8

Study the Role of Green Silver Nanoparticle Against Aspergillus Niger in Adult Albino Male Rats

Laylani Layla Abd-Al-Sattar Sadiq*

Community Health Department. Institute Kirkuk Technical, Northern Technical University, Iraq

*Corresponding author: Layla Abd-Al-Sattar Sadiq Laylani E-mail: doctor.layla@ntu.edu.iq

Online published on 26 September, 2019.

Abstract

The current study was designed to show the role of green silver nanoparticle against toxicity Aspergillus niger. The study used 20 adult albino male rats that distributed randomly to four groups (each group consists 5 rats); control group administrated ad libidium, rats group A. niger, rats group administrated A. niger and treated with 50ug/kg AgNPs, rats group administrated A. niger and treated with 100ug/kg AgNPs. The results levels show significant of MDA high (P < 0.05) (malondialdehyde) and low significant in levels of glutathione (GSH), total antioxidant capacity and catalase compared with the control group. Histological, the sections that prepared from lungs of this group show hemorrhage, thickening walls of alveoli with fibrosis. While, after used rats group administrated A. niger and treated with 50mg/kg AgNPs with A. niger, the results showed non-significant changes (P < 0.05) in MDA, GSH, total antioxidant capacity, and catalase compared with the control group. It was concluded that AgNPs has been potential role against toxicity of Aspergillus niger in adult male albino rats.

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Keywords

Green silver nanoparticle, Aspergillus niger, MDA (malondialdehyde), glutathione (GSH), catalase.

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