Effectiveness of Clindamycin in Treatment of Periodontitis Rieuwpassa Irene Edith1, Achmad Harun2, Rahmasari3 1Lecturer, Oral Biology Dentistry Department, Hasanuddin University, Makassar, South Sulawesi, Indonesia 2Lecturer, Pediatric Dentistry Department, Hasanuddin University, Makassar, South Sulawesi, Indonesia 3Clinical Student, Faculty of Dentistry, Hasanuddin University, Makassar, South Sulawesi, Indonesia Online published on 26 September, 2019. Abstract Clindamycin is a systemically administered antibiotic to support periodontal treatment. Each antibiotic has specifications in destroying microorganisms. Giving prescription drugs for handling a bacterial infectious disease must consider the effectiveness of these antibiotics, therefore to see the level of bacterial sensitivity to certain antibiotics a bacterial sensitivity test is carried out in vitro. It is important to do research to see whether clindamycin is still effectively used for the treatment of periodontitis in patients at RSGM Kandea Makassar. Identification of bacteria from patient samples was diagnosed with periodontitis to obtain Porphyromonas gingivalis (P. gingivalis) and Agregatibacter actinomycetemcomitans (A. actinomycetemcomitans) bacteria in the Microbiology laboratory of the Faculty of Medicine, Hasanuddin University. From 20 samples, A. actinomycetemcomitans were identified in 13 samples and P. gingivalis bacteria in 4 samples. From the disc diffusion test, 8 samples (61.5%) of A. actinomycetemcomitans and 3 samples (75%) of P. gingivalis were still sensitive to Clindamicyn. From these results it can be concluded that clindamicyn antibiotics are still quite effective in killing bacteria that cause periodontitis. Clindamicyn is still an alternative medicine for bacterial infections of the oral cavity. Top Keywords Clindamycin, Treatment Periodontitis. Top |