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Indian Journal of Public Health Research & Development
Year : 2019, Volume : 10, Issue : 9
First page : ( 826) Last page : ( 830)
Print ISSN : 0976-0245. Online ISSN : 0976-5506.
Article DOI : 10.5958/0976-5506.2019.02538.5

Correlated Levels of Anti-Inflammatory Interleukins (IL-4 and iL-10) with Allergic conjunctivitis (Ac) in iraqi Patients

Tektook Nihad Khalawe1,*, Qader Osamah Jihad Abdul2

1Assist Prof., Department of Medical Laboratory Techniques, College of Health and Medical Technics, Middle Technical University, Baghdad

2Assist. Professor, M.B. Ch. B.-F.I.B. Ms. OPHTH.-F.ICO, College of Medicine, Tikrit University, Iraq

*Corresponding Author: Dr. Nihad Khalawe Tektook Department of Medical Laboratory Techniques, College of Health and Medical Technics, Middle Technical University, Baghdad Email: drnihadkhalawe@gmail.com

Online published on 13 November, 2019.

Abstract

Background

Allergic conjunctivitis (AC) is caused by an allergic reaction, most common form was hypersensitivity reaction (type 1), that caused to perennial or seasonal AC. Current study was done in the Hospital of Ibn-AL-Hythem for eyes infections in Baghdad from September-August of 2018, one hundred and thirty-two serum were collected from allergic conjunctivitis patients after diagnostic by a specialist ophthalmologist according to have symptoms, who included 60 male and 72 female, with range age (15–51) years. Used the enzyme-linked immunosorbent assay (ELISA kit) from (Pepro-Tech Company, UK) for estimating levels of both Interleukins (IL-4 and IL-10) in patients serum.

Results

Current study showed higher significant in age group (≥ 35 years) as percentage (57.6%) compare to age group (25–35) as (28.1%), also significantly higher in females (54.5%) than males (45.5%), also level of IL-4 in allergic conjunctivitis patients was (23.91 ± 2.09) compare to control (21.02 ± 2.99), so significantly increased levels of IL-10 in allergic conjunctivitis patients (14.99 ± 2.30) than control (11.10 ± 1.99).

conclusions

Current study were concluded higher significant of allergic conjunctivitis Iraqi patients in age group (≥ 35 years), and the AC in females higher than males, as well as level of IL-4 in allergic conjunctivitis patients were significant with control, and significantly increased levels of IL-10 in allergic conjunctivitis patients compare to control.

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Keywords

Interleukins (IL-4, IL-10), allergic conjunctivitis(AC), Iraqi patients.

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