Association between papilledema and guillian-barré syndrome Kamil Mohammad A.S.1,*, Hatem Aqeel K.2, Abbass Adel M.3, Alhussaini Sajidli.4 1Fallujah University, College of Medicine 2Baghdad University College of Medicine 3AL.hr-rssaiarrl eaching Hospital. Thiear 4Nursing Home Hospital/Medical City *Corresponding author: Dr. Mohammad A.S. Kamil Fallujah University College of Medicine E-mail: mohkamil68@gmail.com 009647707216142.
Online published on 9 January, 2019. Abstract Background Guillain barre syndrome is monophasic acute polyradiculoneuropathy autoimmune in nature, it appears as rapid developing areflexia and motor weakness with or without sensory and autonomic disorder, it reaches nadir in less than 4 weeks. Papilledema is rare and usually asymptomatic finding in patient with GBS, the CSF protein is usually elevated in GBS with papilledema, and high protein level will cause a disorder in the appropriate absorption of CSF at the arachnoid villi. Aim of the study To determine the percent of papilledema in GBS, the causes of papilledema in GBS, the correlation of papilledema to different clinical presentations of GBS. Patients and method A cross sectional study was made on seventy patients who have GBS during 4 weeks hospitalization, males are thirty seven and females are thirty three, that admitted to neurological ward and Respiratory Care Unit in Baghdad Teaching Hospital between 1st January-2017 to 1st January-2018. All patients were newly diagnosed by consultant neurologist and selected according to criteria by Asbury and Cornblath 1990 and meet with Brighton Collaboration Diagnostic Criteria Level 1and 2. Regarding patients who have papilledema diagnosed by consultant neurologist by fundoscopic examination and supported by consultant ophthalmologist by slit lamp examination. Results There is a correlation between GBS and papilledema, in this study 3 patients had papilledema, the percent of papilledema in GBS was (4.29%) and the cause appears to be high CSF protein. Conclusions Regarding the patients who had elevated CSF protein, there is significant association between the presence of papilledema and need for mechanical ventilation. There is more correlation between AIDP and papilledema as compared with (AMAN, AMSAN). Top Keywords Gullian berre syndrome, papilledema, cerebrospinal fluid protein, Acute inflammatory demyelinating Polyneuropathy. Top |