Evaluation Cystatin C Levels and Some Factors of Renal Function in Hypertensive Patients Mohammed Amera Kamal1, Abdul-Mahdi Thanaa2, Hadwan Mahmoud Hussein3,* 1Environmental Research and Studies Centers, Babylon University 2Kirkuk University, College of Pharmacy 3Babylon Technical Institute al-Furat al-Awsat Technical University, Hilla, Iraq *Corresponding author: Mahmoud Hussein Hadwan. Chemistry Dept., College of Science, University of Babylon, Hilla, Iraq, E-mail: mahmoudhadwan@gmail.com
Online published on 2 February, 2019. Abstract The aim of the study is to valuation some biomarker biochemical parameters that play important role in evaluating functions renal for hypertensive. The study was obtained. Included ninety-one. 35(38.46%) of the subjects were males and 56 (61.54%) were females. forty-two (42) subjects were selected as control and forty nine (49) suffered only from essential hypertension with high mean body mass index (Mean 35.70±3.38 S.E) (Kg/m2). The data of the study indicate a signifcant (p’0.05) raise in the rate of age (Mean49.89±10.36) (years), body mass index (Mean 35.70± 3.38 S.E) (Kg/m2), SBP(Mean14.77±0.75 S.E) (mmHg) and DBP(Mean 9.69±0.72 S.E) (mmHg) for patients with hypertensive compared with healthy people. As for the biochemical parameters the results showed a signifcant (p’0.05) increase in concentration serum Cystatin C (Mean1.21 ± 0.44S.E) (mg/L), Creatinine(Mean 1.062±0.36 S.E) (mg/dl), urea (Mean 7.76±0.55 S.E) (mmol/l)and uric acid(Mean 4.77±0.82 S.E) (mg/dl). As for the Correlation coeffcient of linear regression analysis of diastolic blood pressure with the biochemical parameters did not show any signifcant correlation, while the results linear regression analysis showed positive correlation between systolic blood pressure with cystatin C (y= 0.38*×-4.38* SBP), Creatinine(y=0.37*×-4.37*SBP) and uric acid (y=0.1*×-10*SBP). Top Keywords CystatinC, uric acid, creatinine, urea, hypertensive. Top |