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Indian Journal of Public Health Research & Development
Year : 2018, Volume : 9, Issue : 12
First page : ( 943) Last page : ( 948)
Print ISSN : 0976-0245. Online ISSN : 0976-5506.
Article DOI : 10.5958/0976-5506.2018.01970.8

The Antibacterial and Antioxidant Effect of Gold Nanoparticles that repared from Iraqi Mentha Pulegium L

Thyab Rafah M1, Attia Abass J.2, Hadwan Mahmoud Hussein2,*

1Chemistry Dept. Faculty of Science, Kufa University, Najaf City, Najaf Governorate, Iraq

2Chemistry Dept. College of Science, University of Babylon, Hilla City, Babylon Governorate, Iraq

*Corresponding author: Mahmoud Hussein Hadwan Chemistry Dept., Faculty of Science, Kufa University, Najaf City, Najaf Governorate, Iraq; E-mail: mahmoudhadwan@gmail.com

Online published on 2 February, 2019.

Abstract

Medicinal plants are documented as supplies of usual antioxidants that can defend biological tissues from oxidative damage. In current study, the antioxidant status and antibacterial activities of gold nanoparticles (AuNPs) that synthesised by utilizing Mentha pulegium were estimated. Gold nanoparticles (AuNPs) have many potential applications in biomedical and biochemical subjects due to their high biocompatibility and properties and permanency. Chemical reduction activity of plant extract of Mentha pulegium in the synthesis of gold nanoparticles was examined employing UV/visible spectrophotometry, X-ray diffraction (XRD), and Scanning electron microscopy (SEM). Antioxidant activities were determined by using 1, 1-diphenyl-2picrylhydrazyl and cuprac methods. The antioxidant activities of gold nanoparticles (AuNPs) prepared by utilizing Mentha pulegium were elevated. This may be because the high concentrations of the chemical active compounds of Mentha pulegium species that dissolved in the methanol. Mentha pulegium was established to exhibit strong potential for rapid chemical reduction of gold ions. The synthesized gold nanoparticles (AuNPs) exhibited promising antibacterial activity on Escherichia coli and Staphylococcus aureus. The antibacterial activity was obtained for all the strains using methanolic extract synthesized gold nanoparticles (AuNPs). Overall results showed high potential of Mentha pulegium extract to synthesize high quality gold nanoparticles (AuNPs) for biomedical and biochemical applications.

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Keywords

Gold Nanoparticles, Medicinal plants, Antibacterial, Antioxidant.

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