Grading of Metabolic Syndrome Components as Premonitory Denotations for Cardiovascular Diseases Abbas Saja Ali1, Mahmood Majed M.1,* 1Department of Biology, College of Science, Mustansiriya University, Baghdad, Iraq *Corresponding author: Majed M. Mahmood Department of Biology, College of Science, Al-Mustansiriya University, Baghdad, Iraq, E-mail: majidmahmood93@yahoo.com
Online published on 2 February, 2019. Abstract To investigate the magnitude of infammatory events related to metabolic syndrome (MetS) components in Iraqi men, 68 patients with this medical condition (who were diagnosed as being with MetS depending on IDF criteria 2005)11 versus 20 apparently healthy males were enrolled in this study. Patients were divided for three subgroups depending on the number of MetS components they have. All participants were tested for their circulatory levels of certain infammatory markers. Levels of high sensitive C-reactive protein (hs-CRP), interleukin-1β (IL-1β), tumor necrosis factor alpha (TNFα) and interleukin 6 (IL-6) were measured by using ELIZA technique. Triglyceride (TG), high density lipoprotein (HDL-c) and fasting blood sugar (FBS) were measured by using spectrophotometer. Levels of these infammatory markers in the three subgroups of patients were as follow: hs-CRP (7667.817± 486.412 ng/ml) in group I, (6167.548± 575.558 ng/ml) in group II and (5660.655 ± 806.428 ng/ml) in group III, IL-1β (8.624±0.295, 8.240±0.422 and 7.837±0.182pg/ml), TNFα (9.307±0.219 pg/ml, 8.883±0.478 pg/ml and 8.196±0.122 pg/ml) and IL6 (11.428±2.421 pg/ml, 10.373±2.856 pg/ml and 8.452±0.507 pg/ml) respectively, which indicates that the highest clustering of MetS components induce the sturdiest infammatory events. Top Keywords Cardiovascular Diseases, Metabolic Syndrome, Premonitory Denotations. Top |