Analysis of the Association between Sebum Levels and Staphylococcus Epidermidis Infection Identified by PCR in Comedonal, Papular, and Nodular Acne Vulgaris Tabri Farida* Department of Dermatology and Venereology, Faculty of Medicine, Universitas Hasanuddin, Makassar *Corresponding Author: Farida Tabri Department of Dermatology and Venerology Faculty of Medicine Universitas Hasanuddin, Makassar, 90245, HP: 08114104656 Email: farida.tabri.dv@gmail.com
Online published on 2 February, 2019. Abstract Acne vulgaris is a common infammatory disease of pilosebaseous follicles. This study aims to determine the relationship between sebum levels and Staphylococcus epidermidis infection in patients with acne vulgaris through PCR. The study was conducted in Dr. Wahidin Sudirohusodo Hospital, several network hospitals, and several high schools in Makassar City from May 2016 to June 2016. The study used cross sectional research design. The samples were patients aged 15–25 years, with mild, moderate, or severe type of acne vulgaris who came to the dermatovenereology clinic of Wahidin Sudirohusodo Hospital, other network hospital, and several high schools around Makassar City. A total of 45 subjects were identified and were divided into three equal groups each consisting of 15 subjects with mild, moderate, and severe acne, respectively. Samples from comedonal, papulopustular, and nodular lesions were taken followed by examination for Staphylococcus epidermidis infection. The results showed a quite high incidence of Staphylococcus epidermidis infection in acne vulgaris patients, with positive PCR results in 32 out of 45 samples, while 12 samples showed negative PCR results, suggesting Staphylococcus epidermidis as a dominant bacteria in such disease. Top Keywords Acne Vulgaris, PCR, Staphylococcus epidermidis. Top |