The healing of perforated tympanic membrane with nata de coco patch Syahrijuita1,3,*, Kadir Abdul1, Sartini2, Hardjo Marhaen3, Bahar Burhanuddin 1ENT Department of Medical Faculty, Public Health Faculty, Hasanuddin University 2Pharmacy Faculty, Public Health Faculty, Hasanuddin University 3Biochemistry Department of Medical Faculty, Public Health Faculty, Hasanuddin University *Correspondence address: Syahrijuita, Department of ENT-HN, Medical Faculty, Hasanuddin University, Email: syahrijuitakadir@yahoo.com
Online published on 5 November, 2018. Abstract Introduction Perforation of the tympanic membrane is a health problem that cause hearing loss affects the productivity and quality of life. The utilization of the Nata de coco patch (NCP) as an alternative to conservative therapy needs to be done continuously in the experimental animals in its application at human. Objective To know the effectiveness of NCP in accelerating the healing/closing of tympanic membrane perforation due to infection or trauma. Methods Experimental research with complete random sampling of 28 ruptured chicken tympanic membranes divided into 2 groups: NCP group and control group (spontaneous healing). Results Healing of tympanic membrane perforation by using NCP 63% (9 ears) has undergone healing and heals perfectly on day 4th and 100% (14) perforation of the tympanic membrane has been healed on day 6th. While in the control group with spontaneous healing without NCP use only 7.2% (1) perforated tympanic membrane that healed on day 4th and later on the 8th day, 14 (100%) perforated tympanic membrane healed with perfect closured. Conclusion In vivo, NCP has been shown to speed up the healing and closure of perforated tympanic membranes completely compared with non NCP (spontaneous healing). Top Keywords Patch, bacterial cellulosa, perforation, tympanic membrane, laying hen. Top |