Patho-epidemiological study of Streptococcus suis infections in slaughtered pigs from North and North-Eastern Region, India Dinesh Murali1, Thakor Jigarji Chaturji1, Singh Karam Pal2, Singh Rajendra1, Anbazhagan Subbaiyan3, Chauhan Renu4, Qureshi Salauddin4, Sahoo Nihar Ranjan5, Sahoo Monalisa1,* 1Division of Pathology, ICAR-Indian Veterinary Research Institute, Bareilly-243122, India 2Centre for Animal Disease Research and Diagnosis, ICAR-Indian Veterinary Research Institute, Bareilly-243122, India 3Division of Bacteriology & Mycology, ICAR-Indian Veterinary Research Institute, Bareilly-243122, India 4Division of Biological Standardization, ICAR-Indian Veterinary Research Institute, Bareilly-243122, India 5ICAR-International center for Foot and Mouth Disease, Argul, Khordha, Odisha, India. *Address for Correspondence, Dr Monalisa Sahoo, Division of Pathology, ICAR-Indian Veterinary Research Institute, Bareilly-243122, Uttar Pradesh, India, E-mail: vety.lisa@gmail.com
Online Published on 28 July, 2022. Abstract Streptococcus suis, is widely distributed in all pig rearing countries causing huge economic loss to the pork industry. However, the information about the epidemiology of this pathogen with the associated pathologies in Indian pigs is very limited. The study was conducted using pathological, immunohistochemistry, and molecular detection methods from four states of India viz. Uttar Pradesh (Lucknow), Uttar Pradesh (Bareilly), Delhi, Assam (Guwahati), and Punjab (Chandigarh). Out of 664 morbid tissues of slaughtered pigs, 41 cases (6.14%) were found to be positive for S. suis by PCR assay by amplifying gdh gene. The highest rate of prevalence was recorded in Bareilly (24%) while lowest in Guwahati (4.44%). Age wise significantly higher prevalence was recorded in growers followed by finishers. Lungs (58.5%) showed more tropism for S. suis showing predominant pathological lesions of bronchopneumonia. The microscopic lesions in lungs, palatine tonsils, spleen, lymph nodes and brain of naturally affected pigs corroborated well with the distribution of S. suis antigen in these organs on immunohistochemistry. The phylogenetic analysis showed close homology to the isolates of Japan, United Kingdom and China. The study shows that S. suis in slaughtered pigs could be a potential cause of serious public health concern. Top Keywords Immunohistochemistry, Pathology, Phylogenetic analysis, Prevalence, S. suis, Slaughtered pigs. Top |