Comparative Efficacy of Combination Therapeutics for Management of Canine Babesiosis Baishya B.C.1,*, Phukan A., Mahato G.2, Goswami S.3, Kakati P.4 Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary Science Assam Agricultural University (AAU) Khanapara, Guwahati-781022 (Assam) 1Assistant Professor, Department of Epidemiology and Preventive Medicine 2Department of Epidemiology and Preventive Medicine 3Department of Veterinary Pathology 4Ph. D. Scholar, Department of Veterinary Parasitology *Corresponding author. E-mail: bhabenchbaishya@gmail.com
Online published on 4 May, 2019. Abstract Fifty (50) microscopically diagnosed Babesia positive dogs were randomly divided into five treatment groups (B, C, D, E and F) with intention to comparatively evaluate the therapeutic efficacy of single drugs with combination therapy. Parameters were compared with healthy control group A. The dogs of group B were treated with Diminazine diaceturate @ 7 mg/kg b. wt. and dogs of group C were treated with Clindamycin phosphate @ 25 mg/kg b. wt. 12 hourly IV for 14 days were not found effective in treatment compared to dogs of group D treated with combination of Diminazine diaceturate @ 7 mg/kg b. wt. and Clindamycin phosphate @ 25 mg/kg b. wt. 12 hourly IV for 14 days, dogs of group E treated with Doxycycline @ 10mg/kg b. wt. orally daily for 14 days and dogs of group F treated with Diminazine diaceturate @ 7 mg/kg b. wt. and Doxycycline @ 10mg/kg b. wt. orally daily for 14 days. On the basis of microscopic negativity of parasite in the blood smear, mortality rate and improvement of hematological parameters, combination of Diminazine diaceturate and Doxycycline was found most effective for treatment of canine babesiosis. Top Keywords Babesiosis, canine, management, therapeutic. Top |