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Research Journal of Pharmacy and Technology
Year : 2022, Volume : 15, Issue : 12
First page : ( 5555) Last page : ( 5558)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.52711/0974-360X.2022.00938

Anti-inflammatory and Analgesic Studies of 2-aryl-3-(5-alkyl-1, 3, 4-thiadiazol-2-yl) 4-thiazolidinones

Kumar Sunil*, Jain Sandeep**

Drug Discovery and Research Laboratory, Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar (Haryana), India.

*Corresponding Author E-mail: sunilkumar188@gmail.com

**drsjain1969@yahoo.co.in

Online Published on 06 March, 2023.

Abstract

Any damage and bad stimulus causes pain and inflammation. The compound used for pain is known as analgesic and for inflammation is known as anti-inflammatory. The title compounds were evaluated for analgesic activity using Tail-Flick method and anti-inflammatory activity using Carrgenan Induced Rat Paw Edema. Diclofenac Sodium used as standard drug. The chloro, fluro and nitro containg derivatives showed best activity as compared to methyl, methoxy and hydroxy derivatives.

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Keywords

Thiazolidinone, Anti-inflammatory activity, Analgesic activity.

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