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Research Journal of Pharmacy and Technology
Year : 2022, Volume : 15, Issue : 12
First page : ( 5576) Last page : ( 5582)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.52711/0974-360X.2022.00942

3D Bioprinting Models for Novel Breast Cancer Strategies

Ganpisetti Ramesh1,*, Mounika M. Sai2, Bag Indraneel3, Rana Ritika4, Sanjay G.5, Giribabu Ketham6

1Research Scholar, School of PharmacyUniversity of Portsmouth, Portsmouth, UK.

2Department of Zoology, Acharya Nagarjuna University, Andhra Pradesh, India.

3School of Bioscience and Bioengineering, Lovely Professional University, Punjab.

4MSc. Microbial-biotech of Punjab University, Chandigarh, Punjab.

5Advanced Certification in Digital Design Cad, Mindbox and Autodesk, Chennai.

6Department of Pharmacology, Old block, South campus, Andhra University, Visakhapatnam.

*Corresponding Author E-mail: up950648@myport.ac.uk

Online Published on 06 March, 2023.

Abstract

In the last several years developments in biomaterials and tissue technology have opened the door for novel platform technologies in vitro cancer research, particularly the development of bioprinting techniques. Cells, active compounds and biomaterials can be carefully controlled via bioprinting. In light of this, there are new discoveries of safe and effective forms of treatment to fight the prevalence of the deadly malignant diseases, however most are still under clinical trial model but with promising results. One of the major invasive cancers is breast cancer. This is a heterogeneous kind of cancer that is compounded by the presence and return of tiny groups of stem cells that produce chemical or radiation resistance. Cancer models-modelling an experimental methodology to investigate complex biological systems, has significantly subsidized our understanding of cancer. A two-dimensional cell culture model is particularly difficult to investigate in the cancer environment. More physiologically realistic three-dimensional, in vitro cancer models such as spheroid culture, biopolymer bugs, and cancer on-a-chip equipment have been permitted to develop multiple times in tissue technology. It enables customized tissue models of patients' cancers-specific vascular arrangements and immune cells-to be grown in laboratories for testing. Scientists can then examine the models' responses to chemotherapies and other treatments. Bioprinting cancer technology is free from nature, flexibility, customizability, scalability, and consistency, modeling tumor microenvironments with bio printing has a high potential to reduce difficulties. Those studies need to be properly explained and analyzed in a broad way in this review and to help in the progress of cancer research.

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Keywords

Bioprinting, Biopolymer, Tumour, Microenvironment, Technology, Customized.

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