Phytochemical profiling of the Methanolic root extract of Lavaterà cashmeriana using GC- MS and Evaluation of its Potential Antimicrobial Activity Sofi Mohmmad Ashaq1, Nanda Anima1,*, Raj Ezekiel2, Sofi Mohd Abass3 1Department of Biomedical EngineeringSathyabama Institute of Science and Technology, Deemed to be University, Chennai, 600119, Tamil NaduIndia. 2Biocontrol and Microbial Metabolites Lab, Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai – 600025. 3Department of ChemistrySathyabama Institute of Science and Technology, Deemed to be University, Chennai, 600119, Tamil NaduIndia. *Corresponding Author E-mail: animanandabiomed@gmail.com, animananda72@gmail.com
Online Published on 06 March, 2023. Abstract Medicinal plants found worldwide are vast repositories of diverse bioactive phytoconstituents that owe their broad range of medicinal applicability in the treatment, prevention, and diagnostics of diseases. Researchers in the past have successfully tried and are determined in the extraction and purification of phytocompounds which are active agents in treating various alarming to simple diseases and serve as lead compounds in the manufacturing or formulation of novel drugs. The present aim of the research was to conduct the GC-MS analysis of the methanolic root extract of the medically significant plant Lavatera cashmeriana. Through this research analysis, arctigenin is a new compound identified to be present in Lavatera cashmeriana, which was earlier reported and considered to be present in some plant families (Asteraceae, Convolvulaceae and Oleaceae). Meanwhile, the present research was further aimed at evaluating the antimicrobial properties of root extract of this plant on some pathogenic micro-organisms like Enterococcus faecalis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans. The results obtained revealed significant antimicrobial activity of the plant's root extract. Top Keywords Lavatera cashmeriana, Kashmir Himalayas, Gas chromatography-mass spectrometry (GC-MS), Arctigenin, Antimicrobial activity. Top |