Screening of Antifungal Activity of Ganoderma Lucidum extract Against Medically Important Fungi Naveenkumar C1,*, Swathi S2, Jayalakshmi G3, Chidambaram R4, Srikumar R5 1Ph. D Research Scholar cum Assistant Professor, Department of Center for Research, Sri Lakshmi Narayana Institute of Medical Sciences Affiliated to BIHER, Puducherry, Chennai 2Tutor, Department of Center for Research, Sri Lakshmi Narayana Institute of Medical Sciences Affiliated to BIHER, Puducherry, Chennai 3Dean, Department of Microbiology, Sri Lakshmi Narayana Institute of Medical Sciences Affiliated to BIHER, Puducherry, Chennai 4Director R & D, Department of Center for Research, Sri Lakshmi Narayana Institute of Medical Sciences Affiliated to BIHER, Puducherry, Chennai 5Research Associate, Department of Center for Research, Sri Lakshmi Narayana Institute of Medical Sciences Affiliated to BIHER, Puducherry, Chennai *Corresponding author: Mr. C. Naveen Kumar, Ph. D Research Scholar cum, Assistant Professor Department of Microbiology, Sri Lakshmi Narayana Institute of Medical Sciences Affiliated to BIHER, Puducherry, Chennai. Mobile: + 91 9047765601 Email Id: navin.mmb@gmail.com
Online published on 7 February, 2018. Abstract Antimicrobials of plant origin are effective in the treatment of infectious disease while simultaneously mitigating many side effects that are often associated with synthetic antimicrobials. In the present study crude aqueous and ethanolic extract of Ganoderma lucidum was evaluated for its antifungal activity against the clinically important fungi namely Candida albicans, Aspergillus niger, Penicillium marneffei, Cryptococcus neoformans, Trichophyton rubrum, and Microsporum canis. The result showed ethanolic had high inhibitory action against the studies fungus when compared to aqueous extract. In both ethanolic and aqueous extract the maximum inhibition activity was observed against Candida albicans followed by Trichophyton rubrum, Microsporum canis, Aspergillus niger, Penicillium marneffei and Cryptococcus neoformans. Top Keywords Clinically Important Fungi, Ganoderma lucidum, Inhibition Activity, Aqueous and Ethanolic Extract. Top |