Correlation between Calciferol serum Level and Rhinitis Allergy Punagi Abdul Qadar1,*, Ameliyah Ayu1, Rahardjo Sutji P1, Savitri Eka1, Hamid Firdaus2 1Ear Nose Throat Head and Neck Surgery Department, Wahidin Sudirohusodo Hospital, Makassar, Indonesia 2Department of Microbiology, Medical Faculty of Hasanuddin University, Wahidin Sudirohusodo Hospital, Makassar, Indonesia *Author for Correspondence: Abdul Qadar Punagi, Ear Nose Throat-Head and Neck Department, Medical Faculty of Hasanuddin University
Online published on 7 February, 2018. Abstract Background Rhinitis allergy is a global health problem and can disrupt the life quality of the patient. Calciferol is an excellent immunomodulator in inhibiting IL-4, IL-5 and IL-13 and will reduce Th2 differentiation. Objective The objective of this study is to determine the correlation between calciferol serum level and rhinitis allergy symptoms. Methods This study include 40 subjects with cross sectional design to determine the correlation between calciferol serum level and rhinitis allergy symptoms in rhinitis allergy patients based on total nasal symptom score (TNSS). TNSS for very mild = 0–2, mild = 3–6, moderate = 7–9, and severe = 10–12. Statistical analysis was done by using univariate linear regression test and multivariate linear regression test with p<0.05. Results Calciferol serum level has significant correlation with age and rhinitis allergy symptoms based on TNSS which is analysed by univariate linear regression test (p<0.05). The result in multivariate linear regression test suggest a strong correlation between calciferol serum level and rhinitis allergy symptoms based on TNSS (p<0.05). Conclusion Calciferol serum level has significant correlation with rhinitis allergy symptoms based on TNSS. Control of calciferol serum level can be considered as an effort to improve the health of rhinitis allergy patient. Further study that emphasise in controlling calciferol serum level should also consider in controlling rhinitis allergy symptoms. Top Keywords Rhinitis allergy, calciferol serum, total nasal symptom score. Top |