Year : 2023, Volume : 12, Issue : suppl
First page : ( 147) Last page : ( 147)
Print ISSN : 2320-1193. Online ISSN : 2394-448X. Published online : 2023 December 12.
Article DOI : 10.5958/2394-448X.2023.00065.2

Application of the Peptide Nucleic Acid Blocker to Improve the Sensitivity of Real-Time PCR for Quantitating JAK2 V617F Mutation

Nguyen Tuan-Anh^1,2,*, Vu-Thi Hai-Yen^3,4, Huynh-Thi Thu-Thao^3,4, Nguyen-Thi Nga³, Ha-Thi Anh³, Ha Manh-Tuan^1,2,5, Nguyen-Van Hoang-Son⁶, Vilaivan Tirayut⁷

¹Molecular Biomedical Center, University Medical Center Ho Chi Minh City, Ho Chi Minh City, Vietnam

²University Medical Center Ho Chi Minh City - Campus 2, Ho Chi Minh City, Vietnam

³Hong Bang International University, Ho Chi Minh City, Vietnam

⁴University of Natural Science, Vietnam National University Ho Chi Minh City, Ho Chi Minh City, Vietnam

⁵University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam

⁶iLab Medical Center, Ho Chi Minh City, Vietnam

⁷Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand

^*Corresponding Author: anh.nt@ume.edu.vn

Online Published on 12 December, 2023.

Received:  30  October,  2023; Accepted:  12  November,  2023.

Keywords

Blocker, JAK2 V617F, Peptide nucleic acid, Polycythemia vera, Real-time PCR.

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