Management of non-hospitalized patients with Acute SARS-CoV-2 (COVID-19) viral infection in among human adult population Singh Pumila1, Sharma Divya1, Singh Varsha1, Kumari Sheila1, Singh Arjun2,*, Jain Hema1 1Department of Pharmacology, School of Pharmaceutical Sciences, Bhagwant University, Sikar Road, Ajmer, Rajasthan, 305004, India 2Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, 19107, United States *Corresponding Author E-mail: arjunphar@gmail.com
Online Published on 24 January, 2024. Abstract The global corona virus disease outbreak, also known as the COVID-19 pandemic outbreak, caused a major health crisis around the world. The morbidity and mode of transmission of COVID-19 appear to be more severe and uncontrollable. The main pathophysiology of this deadly disease is respiratory failure and subsequent cardiovascular complications. From a pharmacological standpoint, several therapeutic strategies have been proposed for the development of safe and effective treatment against the SARS-CoV-2 virus, but no specific treatment regimen has been developed for this viral infection to date. The current review focuses on the role of herbs and herbs-derived secondary metabolites in inhibiting the SARS-CoV-2 virus as well as in the management of post-COVID-19 complications. This strategy will promote and protect the use of medicinal plant resources to support the healthcare system. Plant-derived phytochemicals have already been shown to prevent viral infection and to alleviate post-COVID complications such as parkinsonism, kidney and heart failure, liver and lung damage, and mental problems. We investigated mechanistic approaches of herbal medicines and their phytochemicals as antiviral and post-COVID complications by modulating immunological and inflammatory states in this review. Top Keywords SARS-CoV-2, Coronavirus, Natural products, Outbreak, Herbal medicine. Top |