Asian Journal of Multidimensional Research (AJMR)
Year : 2019, Volume : 8, Issue : 2
First page : ( 157) Last page : ( 164)
Online ISSN : 2278-4853.
Article DOI : 10.5958/2278-4853.2019.00043.0

Features of coagulation and cellular hemostasis in rheumatoid arthritis in patients with cardiovascular pathology

Naimova N. Sh., Umurova N.M., Avezova Z.B., Egamova S.Q.

Bukhara State Medical Institute, Uzbekistan

Online published on 4 March, 2019.

Abstract

The article presents materials about effect of rheumatoid arthritis (RA) on the parameters of the hemostatic system in patients with cardiovascular pathologies. In order to study this work, 94 patients with RA were examined with an associated CVD and hemostasis was compared with a group of RA without CVD, which consisted of 40 patients. The influence of age, sex, and activity of the RA on the hemostasis indicators of this category of patients was analyzed. The activation of all links of hemostasis in patients with RA and CVD was found in comparison with those with RA without CVD. The data we obtained confirm that chronic inflammation leads to violations of the blood coagulation system in the direction of hyper coagulation and subsequently to thrombosis and the more seniority and age of patients with RA + CVD and the higher the activity of inflammatory joint disease, the more pronounced the changes in coagulation hemostasis towards hyper coagulation.

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Keywords

Rheumatoid Arthritis, Inflammation, Hemostasis, Cardiovascular Diseases, Cardiovascular Risk.

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