Clinical features and forecast of ischemic heart disease in patients with metabolic syndrome (Review) Rajabova G.X., Soliev A.U., Jumaev K. Sh. Bukhara State Medical Institute, Uzbekistan Online published on 16 October, 2019. Abstract Chronic heart failure (CHF) is a major medical and social problem. The increase in morbidity is due to both an increase in the life expectancy of the population and the influence of risk factors that contribute to the development and increase of circulatory failure. The combination of several atherogenic factors (abdominal obesity, insulin resistance, arterial hypertension, hyperglycemia, dyslipidemia), combined by the concept of “metabolic syndrome” (MS), leads to a more rapid development of heart failure. The article presents the data of several large-scale studies that were aimed at the presence of close relationships between obesity, arterial hypertension (AH), hyperlipidemia, impaired glucose tolerance and cardiovascular diseases. Coronary heart disease-a disease of the heart muscle caused by an imbalance between the coronary (coronary) blood flow and the metabolic needs of the heart muscle. This formulation was proposed by a team of specialists in the study of atherosclerosis and coronary heart disease in 1957.. MS is characterized by an increase in visceral fat mass, a decrease in the sensitivity of peripheral tissues to insulin and hyperinsulinemia, causing the development of a combined pathology of internal diseases (polypathy), disorders of carbohydrate, lipid, purine metabolism and arterial hypertension (AH) [James P.T. et al., 2004; Jorgensen M. et al, 2004]. Women with metabolic syndrome were over 50 years old. Diabetes mellitus and obesity, as components of MS, were more common among women, while men showed a tendency to higher triglycerides and low HDL. Thus, despite the active study of MS, many controversial issues remain, which requires further research in this area. According to foreign and domestic authors, patients with MS and type 2 diabetes are characterized by multiple and distal vascular lesions (M. G. Lee, M. H. Jeongetal., 2008; Shishkin A.N., Droganova A.S., 2014). Top Keywords Metabolic Syndrome, Chronic Heart Failure, Risk Factors, Arterial Hypertension, Ischemic Heart Disease. Top |