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Asian Journal of Pharmaceutical Research
Year : 2023, Volume : 13, Issue : 3
First page : ( 163) Last page : ( 168)
Print ISSN : 2231-5683. Online ISSN : 2231-5691.
Article DOI : 10.52711/2231-5691.2023.00031

A Review on Microspheres as Controlled Release Drug Delivery

Paul Malay*, Keerthy H. S, Sharma Mukesh, Patel Pradeep Kumar, Sowmya TP

Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore – 560090

*Corresponding Author E-mail: paulmalay550@gmail.com

Online Published on 04 October, 2023.

Abstract

Microspheres play a totally critical function as a particulate drug transport machine due to theirtiny size and different properties. Microspheres proved an appropriate bridge to scale the gap over to formulate a powerful dosage form, to managed drug release, to simulate controlled drug release. Microspheres are often free-flowing stable powders, which include proteins or artificial polymers, which can be biodegradable. Microspheres having a particle size in the range of 0.1-800µm, can be delivered by several routes like oral, parenteral, nasal, ophthalmic, transdermal, colonal, etc. Various recent advancements in the case of microspheres like mucoadhesive, hollow, floating, micro balloons, and magnetic have contributed to overcoming the diverse troubles which might be related to using microspheres, which incorporates site-precise focused on and stepped forward release. In the future by combining various new designing, planning’s, and strategies, microspheres will find a central place in novel drug delivery, especially in diseased molecular sorting, genetic materials, safe, targeting, and powerful drug delivery.

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Keywords

Microspheres, Controlled release, Methods of preparation, Polymer, Applications.

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