Benzimidazole: An important Scaffold in Drug Discovery Preethi P. Jaya*, Karthikeyan E., Lohita M., Teja P. Goutham, Subhash M., Shaheena P., Prashanth Y., Sai Nandhu K. Department of Pharmacy, Sree Vidyanikethan College of Pharmacy, Tirupati, India *Corresponding Author E-mail: jayapeesa@gmail.com
Online published on 29 January, 2016. Abstract Benzimidazole is the heterocyclic compound formed by the fusion of benzene and imidazole ring. Benzimidazole derivatives belong to a crucial structural design that is seen in many pharmaceutically and biologically interesting molecules. Benzimidazole has shown potential for application in a variety of pharmacological targets. They have been intensively used in medicinal chemistry as drugs such as antihistaminic, antiulcerative, antihelmentic, antipsychotic etc. Benzimidazole is outstandingly effective compounds and there are a number of reviews available for biochemical and pharmacological studies which confirmed that these molecules are useful against a wide variety of microorganisms. For these reasons, they achieved much attention as important pharmacophore and privileged structure in medicinal chemistry. This review summarizes to know about the different derivatives of Benzimidazole. Top Keywords Pharmacological activities, Substituted Benzimidazole, Benzimidazole derivatives. Top |