Design and Synthesis of Some Novel Chalcones as Potent Antimicrobial Agent Baviskar Bhagyesh1,*, Patel Sureshbhi1, Baviskar Bhushan2, Khadabadi SS2, Shiradkar Mahendra3 1Department of Chemistry, S. P. D.M. Art, Science, Commerce College, Shirpur – 425 405, (M.S.), India 2Department of Pharmaceutical Chemistry, Government College of Pharmacy, Amravati – 444 604, (M.S.), India 3Sai Adventerium Pharmaceutical Ltd, Hydrabad, (A.P.), India *Corresponding Author E-mail: baviskarbhushan@gmail.com
Online published on 13 March, 2013. Abstract Some novel chalcones were synthesized by condensation of N-(4-phenylthiazol-2-yl) acetamide with aromatic aldehydes in presence of aqueous potassium hydroxide solution at room temperature. All the title compounds characterized on the basis of their IR, 1H NMR spectroscopic data and elemental analysis. All the compounds have been screened for antimicrobial activity by the cup-plate method. Top Keywords Synthesis, Thiazole, Chalcones, Aldehydes, Antimicrobial activity. Top |