Genetic Relationship of Transcriptional Factor Genes in the Regulation of Cells Death in Arabidopsis: A Review Khaskheli A.J.1,2*, Zhang L.1, Khaskhel M.I.3, Khaskheli A.A.4, Qing L.H.1 1Institute of Cell Biology and Ministry of Education, Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou730000, China. 2Department of Biotechnology, Faculty of Crop Production, Sindh Agriculture University, Tandojam, Pakistan. 3Department of Plant Protection, Faculty of Crop Protection, Sindh Agriculture University, Tandojam, Pakistan. 4Department of Animal Nutrition, Shaheed Benazir Bhutto University of Veteirnary and and Animal Sciences, Sakrand, Pakistan. *Corresponding Author: A.J. Khaskheli, Institute of Cell Biology and Ministry of Education, Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou730000, China. Email: aajkhaskheli2012@gmail.com.
Online published on 24 January, 2022. Abstract The leaf yellowing is the first visible sign of senescence, which starts at the margins of the leaf and progresses to the blade. Although, transcriptional factor family genes generally encode meticulous regulators which perform a range of functions in turns regulating the physiological and developmental mechanism of plant stature. However, the genetic relationship of TFs genes in regulating the cell death of Arabidopsis is well not understood to date. TFs family in a plant regulates various developmental and stress responses in underline pathways. In our review we observed the genetic relationship of TFs genes in regulations of cell death in Arabidopsis. Given that, programmed cell death (PCD) being an active process that includes the expression of hundreds of genes. It is speculated that many TFs are involved in the core elements of the regulatory network. There are only a few factors that are being demonstrated in involving the regulation of cell death, by evaluating the leaf senescence appearances of knocking of mutants and by identifying downstream target genes. In this review, we have focused on the manifold roles of TFs during genetic relationships and the regulation of cell death in Arabidopsis. We also deliberated how the transcription factors family gene regulates the cells’ death by different hormonal stress, environmental strain and their role in retrograde signaling. For deep understanding of regulatory molecular mechanisms of cell death in the plant, future research may be hypothesized to collect appropriate evidence and a detailed study may be implemented on the upstream pathway with a specific targeted gene that recognizes the stress signals involved in cell death in plants. Also, crosstalk between mitochondria and chloroplast is mainly being focused to better understand the regulations of cell death in plants. Present review concludes that regulating the cell death of Arabidopsis is very important for meeting future global food needs, crop yields. Overexpression of ERF transcription factors genes relating cell death of Arabidopsis confers broad-spectrum resistance to pathogens and other abiotic stresses and can also make transgenic plants resistant to drought, salinity and freezing. Top Keywords Arabidopsis, AP2/ERF, Cells death, Stress, Transcriptional regulation. Top |