Phytochemistry and gas chromatography-mass spectrometry (GC-MS) analysis of bioactive components of methanolic root-bark extract of Boswellia dalzielii (burseraceae) Mamza U.T.1,*, Rabiu M.1, Khan S.2, Shah M.3, Arshad M.4, Yakubu J.1, Dawa S.I.5, Sule I.1, Khan I.Z.1 1Department of Pure and Applied Chemistry, University of Maiduguri, Borno State, Nigeria 2Suny Downstate Health Sciences University, Department of Pediatrics Children's HospitalNew York, USA 3Parsons 10625 Rd, Johns Creek, GA30097Atlanta, USA 4Study Hall, Vipul Khand, Gomti, Nagar, Lucknow, Uttar Pradesh226010, India 5Department of Chemistry, Borno State University, Maiduguri, Borno State, Nigeria *Corresponding Author Dr. U.T. Mamza, Department of Pure and Applied Chemistry, University of Maiduguri, Borno State, Nigeria E-mail: utmamza@unimaid.edu.ng, drutmamza_2587@yahoo.com
Online published on 6 July, 2022. Abstract This study was conducted to identify phytochemical constituents present in the methanolic root-bark extract of B. dalzielii using GC-MS analysis and conventional phytochemical evaluation. The studies revealed the presence of alkaloids, flavonoids, saponins, cardiac glycosides, terpenoids and carbohydrates. A total of forty three compounds composed of eighteen major components were identified thus; oxetane-2,3,4-trimethyl (3.45%), Bicyclo[4.1.0] heptan-3-one-7,7-dimethyl-4-methylene(IR) [2.69%], 2-methyl-2-(−2-oxopropyl) furan (3.20%), Cyclohexane, 2-(dimethylhydrazono)-3-[4-hexenyl]-1-acinitro,(E,) [2.63%], 3,8-Dihydroxy-3,4-dihydronaphthalen-1(2H)one (4.43%), 2-Tetradocanol (4.89%), 3-methyl-2-(2-oxopropyl)furan (3.46%), (2H)-Naphthalenenone, 6-(1,1-dimethyl ethyl) octahydro-2,8a-dimethyl (3.80%), Pentadecanoic acid (6.18%), undecanoic acid (3.68%), Phthalic acid (4.14%), 1-Allyl-cyclohexane-1,2-diol (3.95%), 1,5,9-cyclotetradecatriene, 1,5,9-trimethyl-12-(1-methyl ethyl) [4.58%], 9,12-octadecadienoic acid (Z,Z)-methyl ester (4.75%). 9-octadecenoic acid, methyl ester[E] (4.36%), Tetradecanoic acid-methyl ester(S) [3.90%], (2S,4R)-p-mentha-[1(7),8]-diene-2-hydroperoxide (2.62%) and 1-Naphthalenepropanol, a-ethyldecahydro-8a-(hydroxymethyl)-a, 5-dimethyl-2-methylene (2.93%). Most of the identified compounds have been reported to possess various biological activities such as antimicrobial, anti-inflammatory, antimalarial, antidiabetics, anti-asthmatic, anti-histamine, antitubercular, anti-diarrhoeal among others. The studies thus concluded that B. dalzielii root-bark possesses potent bioactive compounds and is recommended as a plant of phytopharmaceutical importance. The presence of these bioactive compounds justifies the use of this plant in ethnomedicine. Top Keywords Phytochemistry, GC-MS Analysis, Bioactive compounds, Root-bark extract, Boswellia dalzielii. Top |