Establishment of reference intervals of thyroid function test in healthy individuals Marwah Simbita1, Mehta Mihir2,*, Raval Charmi3, Trivedi Amit4, Haridas N.5 1Associate Professor, Parul Institute of Medical Sciences and Research, Vadodara, Gujarat, 2Assistant Professor, SBKS Medical College, Vadodara, Gujarat, 3Student, Pramukhswami Medical College, Gujarat, India 4Assistant Professor, Pramukhswami Medical College, Gujarat, India 5Professor, Dept. of Biochemistry, Pramukhswami Medical College, Gujarat, India *Corresponding Author: Email: mihirac2006@gmail.com
Online published on 2 January, 2019. Abstract Aim The central role of the laboratory is to aid the clinician, in interpreting observed values, by providing relevant reference values. To prevent ambiguities inherent in the term normal values, a laboratory should establish its own reference limits. Therefore, the current study was aimed at establishing the reference range of Thyroid function test in healthy population. Study Design This was a retrospective cross sectional study on 1000 healthy individuals above 18 years of age, attending the routine health check-up. Materials and Methods Partitioning was done according to age and sex, inclusion and exclusion criteria were applied and T3, T4 and TSH levels were estimated on the study group. Results The values of T3 and T4 obtained were (mean and reference interval in nmol/L) 1.85 (1.15–2.55) and 100.58(57.35143.81)respectively for males and 1.87(1.07–2.55) and 110.49(62.46–158.52) respectively for females. Similarly, TSH values were 1.23 (0.37–5.19) mIU/L and 1.37(0.27–5.63) mIU/L in males and females respectively. Conclusion We found that the value of serum Total T3 & serum Total T4 was higher as compared to the international values while that serum TSH was similar. ¡Top Keywords Reference range, T3, T4, TSH. Top |