Study of iodine nutrition level in pregnant south Indian subjects in third trimester Pichandi Suresh1,*, Janakiraraman P.2, Ramadevi K.3 1Assistant Professor, Dept. of Biochemistry, Velammal Medical College Hospital & Research Institute, Madurai, Tamil Nadu, 2Tutor, Dept. of Biostatistics and Community Medicine, PES Medical College, Kupam, Andhra Pradesh, 3Professor, Dept. of Biochemistry, Madras Medical College, Chennai, Tamil Nadu, India *Corresponding Author: Email: sureshchanth82@gmail.com
Online published on 2 January, 2019. Abstract Objective Aim of the present study is to analyse the nutritional status of iodine among pregnant women by measuring urinary excretion and do the correlation with thyroid hormone and auto antibodies Materials and Methods one hundred pregnant women with third trimester gestation and one hundred age-matched nonpregnant were included in study. Results Urinary Iodine excretion and serum TSH, fT4, fT3, AMA and ATG were estimated were estimated for case and control groups. The mean urinary iodine excretion concentration (UIC) in pregnant women was 290.17±91.71 μg/L. Excess urinary iodine excretion was found in 69%. There were elevated serum AMA levels in 36 pregnant women and that positive correlated with excess iodine. Conclusion The pregnant women had no iodine deficiency, rather had high urinary iodine concentrations indicating more than adequate iodine intake. The excess urinary iodine level may tiger the thyroid auto antibody. Top Keywords Urinary iodine excretion (UIE), Thyroid stimulating hormone (TSH), Free thyroxine (fT4), Free tri-iodothyronine (fT3), Anti-microsomal antibody (AMA), Anti-thyroglobulin antibody (ATA), pregnancy, Iodine excess. Top |