Periodontal Regeneration from Illusion to Reality Badar Sheikh Bilal1,*, Javed Faizan1, Ghafoor Robia2 1Resident, Dental Section, Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan 2Assistant Professor and Section Head, Dental Section, Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan *Corresponding Author: Dr. Sheikh Bilal Badar, Resident Operative Dentistry, Mailing Address: Dental Clinics, Aga Khan University Hospital, P.O Box 3500, Stadium Road, Karachi, 74800, Pakistan, Email: sbilalbadar@gmail.com, sheikh.badar@aku.edu, Tel: 0092-213-4866467, Fax: 0092-213-4934294, Mobile #: 0092-345-2388775
Online published on 6 April, 2019. Abstract Periodontitis affects tooth supporting structures which results in tooth loss. In order to restore these supporting structures various regenerative surgical modalities have been proposed which include mechanical and biologic approaches. The mechanical approaches have shown limited success as opposed to biologic approaches. The biologic approaches include guided bone regeneration, enamel matrix derivatives, stem cells etc. Recent approaches include stem cell based and scaffold based tissue engineering. The stem cells derived from periodontal ligaments, dental pulp and alveolar periosteum have shown to develop into various components of periodontium in multiple animal studies. Therefore, periodontal regeneration is becoming a reality, however, its implication in clinical dentistry still needs evidence from human studies. Top Keywords Periodontal regeneration, periodontitis, tissue engineering, periodontal regenerative techniques. Top |