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International Journal of Contemporary Pathology
Year : 2019, Volume : 5, Issue : 2
First page : ( 37) Last page : ( 41)
Print ISSN : 2394-790X. Online ISSN : 2395-1184.
Article DOI : 10.5958/2395-1184.2019.00028.7

Retrospective Study of Metastasis in Lymph Node by Fine Needle Aspiration Cytology

Das Mitali L.1,*, Shah Ina B.2, Goswami Hansa M.3

1Post-graduate Resident, Department of Pathology, B. J. Medical College and Civil Hospital, Asarwa, Ahmedabad, Gujarat, India

2Associate Professor, Department of Pathology, B. J. Medical College and Civil Hospital, Asarwa, Ahmedabad, Gujarat, India

3Professor & Head, Department of Pathology, B. J. Medical College and Civil Hospital, Asarwa, Ahmedabad, Gujarat, India

*Corresponding author: Dr. Mitali L. Das, Postgraduate Resident of Pathology, B. J. Medical College and Civil Hospital, Asarwa, Ahmedabad-380016, Gujarat, India. E-mail mitalilalu1991@gmail.com, Phone number +919512248935

Online published on 17 July, 2019.

Abstract

Introduction

Fine needle aspiration cytology (FNAC) is a reliable as well as an inexpensive diagnostic method. It is suitable for the developing countries for the diagnosis of lymphadenopathy at any approachable site. Fine needle aspiration cytology not only confirms the presence of metastatic disease but also, in most cases, gives the clue regarding the origin of the primary tumor, prognosis as well as in the management of patient for staging purposes. The aim of the study was to detect and diagnose metastasis in lymph nodes.

Material and Method

Total 180 cases of metastatic lesions of the lymph node were studied from January 2017 to December 2018 by Fine Needle Aspiration Cytology in cytology section, department of pathology, B.J.Medical college, Ahmedabad. Aspiration was done by using 22–24 gauge disposable needle and 10 ml syringe. Both wet fixed and air dried smears were used. Smears were stained with papanicolaou, Hematoxyline and eosin and May-Grunwald-Giemsa stains.

Result

A total of 1175 cases of lymph node fine needle aspiration cytology were carried out of 180 cases were positive for metastasis. The most common site was cervical lymph nodes. Maximum numbers of cases of metastatic tumors were in 41–60 yrs age group(63.89%). There were 122 males and 58 females with a male predominance (Male:Female= 2.1:1). The most common malignancy was squamous cells carcinoma, seen in 108 cases (60%), followed by metastatic adenocarnicoma carcinoma (25 cases, 13.87%).

Conclusion

FNAC is a rapid, safe and cost-effective technique. It gives early and accurate results with minimal invasion and reduces the need for surgical biopsies, thus saves cost and time to reach the final diagnosis. It is therefore concluded that FNAC is a useful tool in diagnosing metastatic lesions of lymph nodes with a good certainty.

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Keywords

Fine needle aspiration cytology, Lymphadenopathy, Metastasis, Squamous cell carcinoma.

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