A Study of Urinary Tract Infections in Patients with Catheter in Tertiary Care Hospital in Western Uttar Pradesh Dimri Sanjeev1,*, Sharma Hemant2, Datta S K3, Gupta Deepak1 1Assistant Professor, Department of Microbiology, Saraswathi Institute of Medical Sciences, Hapur, Uttar Pradesh, India 2Assistant Professor, Department of Medicine, Saraswathi Institute of Medical Sciences, Hapur, Uttar Pradesh, India 3Professor and Head, Department of Microbiology, Saraswathi Institute of Medical Sciences, Hapur, Uttar Pradesh, India *Corresponding author: Sanjeev Dimri, Assistant Professor, Department of Microbiology, Saraswathi Institute of Medical Sciences, Hapur, Ghaziabad, U.P. India, Tel: +91 9958322747, E-mail: sdimri1966@yahoo.co.in
Online published on 7 October, 2013. Abstract Aim The aim of this study was to determine microorganisms responsible for urinary tract infections (UTI) in patients with indwelling urinary catheter and their antibiotic susceptibility patterns to commonly used antibiotics. Subjects and Method The study was carried out from April 2011 to January 2012 on 108 patients with indwelling urinary catheters. The organisms were isolated by conventional culture methods and identified by conventional biochemical methods. The antibiotic susceptibility pattern was determined by Kirby-Bauer disc diffusion method on Muller-Hinton agar. Results In this study, 93 (86.1%) patients were found to be culture positive for microbial pathogens in their urine samples. Escherichia coli (50.5%) was the most frequently isolated bacteria followed by Klebsiella species (14%) and Pseudomonas aeruginosa (10.8%). The in-vitro susceptibility pattern of frequently isolated gram negative bacteria shows high resistance to commonly used antibiotics such as ampicillin, amoxicillin+clavulanic acid and fluoroquinolones. Carbapenems and amikacin were found to be the most effective antibiotics for frequently isolated gram negative bacteria. Conclusion Emphasis should be placed on good catheter management rather than using prophylactic antibiotic therapy to reduce the incidence of catheter associated urinary tract infection. Top Keywords Catheter, CAUTI, Pathogen, Kirby- Bauer, Resistance. Top |