The association between lead exposure and childhood asthma: A systematic review Farkhondeh T1, Samarghandian S2,*, Azimi-Nezhad M2 1Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand. Iran 2Department of Basic Medical Sciences, Neyshabur University of Medical Sciences, Neyshabur. Iran *Corresponding author: Saeed Samarghandian, Department of Basic Medical Sciences, Neyshabur University of Medical Sciences, Neyshabur, Iran. Email: samarghandians1@nums.ac.ir
Online published on 13 December, 2018. Abstract Asthma in children is a complex disorder that many different types of environmental agents are considered as its risk factors. The purpose of the present study was to do a systematic review of the studies demonstrating the relation of lead exposure and childhood asthma. A review of the studies up to May 2018 was done using key words agreed by the research team. The abstracts were evaluated and suitable papers selected to review. Papers demonstrating the relation of lead exposure and childhood asthma were considered. Results: 154. abstracts were identified, 82 papers reviewed and 5 papers included in the present review of which 4 were cross sectional studies and 1 study was cohort. There was not strong evidence that indicated the lead exposure and asthma in children. Due to methodological differences, we suggest to do the international, multicenter, multiethnic studies with larger sample size to evaluate the association between lead exposure and asthma. Top Keywords Lead exposure, Lead poisoning, Asthma, Children, Heavy metal. Top |