Evaluation of diagnostic value of amniotic fluid ferritin and its relation to the pregnancy complications Rezaie-Keikhaie Khadije1,*, Moshfeghi Maryam2, Kazemi Zohreh3, Rezaie-Kahkhaie Leili4 1Associate Professor, Department of Obstetrics and Gynecology, Medicinal Herbs Research Center, Zabol University of Medical Sciences, Zabol, Iran 2Assistant Professor, Royan Institute-Department of Endocrinology and Female Infertility, Reproductive Biomedicine, Research Center, ACECR, Tehran, Iran 3Assistant Professor, Department of Obstetrics and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran 4Assistant Professor, Medicinal Herbs Research Center, Zabol University of Medical Sciences, Zabol, Iran *Corresponding Author: Leili Rezaie-kahkhaie, Medicinal Herbs Research Center, Zabol University of Medical Sciences, Zabol, Iran. Email: abasetmalekrn@gmail.com
Online published on 13 December, 2018. Abstract Introduction The first step in preventing pregnancy complications is the early identification of women at risk and treatment for these women during prenatal care; therefore, a proper diagnostic and screening test that is inexpensive and useful for all pregnant women is necessary. Method The present descriptive-analytical study was conducted on all pregnant women referring to the clinic of Ami al-Momenin Hospital of Zabol in 2016. The inclusion criteria include pregnant mothers with the gestational age of 20 weeks, singleton pregnancy, and willingness and satisfaction to enter the study. Results In the present study, the mean level of ferritin in women suffering from preeclampsia was 92.25±14.81. The mean level of ferritin was significantly higher than that of the healthy women in the control group. the mean level of ferritin in women suffering from diabetes was 33.28±8.38. However, the mean level of ferritin in diabetic women was not significantly different from that of the healthy women in the control group. The mean level of ferritin in women suffering from oligohydramnios was 46.0±10.29., the mean level of ferritin in women suffering from placental abruption was 35.5±9.19. The mean level of ferritin in women suffering from premature rupture of membranes was 88.90±15.32. Conclusion The findings of the present study indicate that the mean level of ferritin in women suffering from preeclampsia as well as women with premature rupture of membranes were significantly higher than that of healthy women having no pregnancy complications. However, the ferritin level of women with other pregnancy complications (including pregnancy diabetes, fetal abnormalities, placental abruption, and oligohydramnios) was not significantly different from that of the healthy women in the control group. Top Keywords Ferritin, Amniotic Fluid, Pregnancy. Top |