Post Traumatic Fibrous Dysplasia of Ribs at the Chest Tube Site (A Case Report) Mousavie Seyed Hamzeh1, Hosseinpor Parisa2, Mardani Azam3, Moradi Alireza1, Arminfard Amirhossien4, Abbasnejad Vahid4, Farazmand Behnood4,* 1Assistant Professor of General Surgery, Rasool-akram Hospital, Iran University Medical Sciences, Tehran, Iran 2Medical Student, Rasool-akram Hospital, Iran University Medical Science, Tehran. Iran 3Resident of Pathology, Rasool-akram Hospital, Iran University Medical Science, Tehran. Iran 4Resident of General Surgery, Rasool-akram Hospital, Iran University Medical Science, Tehran, Iran *Corresponding Author: Behnood Farazmand, MD. Iran University of Medical Sciences, Tehran, Iran. E-mail: behnood.farazmand@iran.irbone
Online published on 7 May, 2019. Abstract Fibrous Dysplasia (FD) is a benign non-inherited and rare skeletal disorder that can affect any bone of human body. FD is caused by a mutation in GNAS1 gene, but the mutation is not inherited from parents. While there are some reports of post-traumatic fibrous dysplasia, but the relationship between fibrous dysplasia and trauma or previous injury is unclear. Most of the time, fibrous dysplasia is diagnosed by accident in x-ray imaging. While there is much information on fibrous dysplasia, the main etiology is still unknown, however it seems to be linked to a gene mutation. A mutation in this gene affects differentiation and proliferation of cells. This benign fibro-osseous lesion is a result of disturbances of normal bone metabolism by a mutation of the alpha subunit of guanine nucleotide binding protein alpha stimulating. Here we report a case with two adjacent ribs involvement in a 25-year old man who admitted to our hospital with an acute right chest pain and swelling with history of major trauma in a motor vehicle accident 4 years ago with associated hemo-pneumothorax resulted in thoracostomy tube insertion and with subcutaneous mass was detected in the right chest wall which was located exactly at the thoracostomy tube insertion site. Top Keywords Fibrous Dysplasia, Trauma, Chest Tube, GNAS1. Top |