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Indian Journal of Forensic Medicine & Toxicology
Year : 2019, Volume : 13, Issue : 2
First page : ( 301) Last page : ( 306)
Print ISSN : 0973-9122. Online ISSN : 0973-9130.
Article DOI : 10.5958/0973-9130.2019.00135.X

Histological & Physiological Alternations in the Aorta & Heart in Relation with Cholesterol Diet in Male Albino Rat

AL-Aameli Muna Hussain1,*, Al-Taee Rajaa Ali Moheiseen2, Alsalame Heba A. Abd-Alsalam3

1College of Veterinary Medicine, Kerbala University, Iraq

2College of Medicine, Babylon University, Iraq

3College of Education for Pure Science, Kerbala University, Iraq

*Corresponding author: Muna Hussain AL-Aameli. College of Veterinary Medicine, Kerbala University, Iraq

Online published on 7 May, 2019.

Abstract

The aim of this work was to examine the microscopically alterations in the heart architecture & of albino rat & physiological aspects of lipid profile in relation with cholesterol diet. Ten male of albino rats were subdivided into two groups (n=5): group 1 was given 1 ml of normal saline & considered as control group(G1), while the second group treated with enriched-cholesterol nutriment once at a dosage of 1.5 mg/k g body weight extent to 8 weeks & considered as treated group(G2). The tissues of hearts & aortic were obtained & stained with H & E stain. Blood samples were withdrawn after starvation of the animals at night after the end of the experiment to study the following parameters: measurement the intensification of (T C), (T A G), (H D L), (L D L) & (V L D L). Result showed the presence of a significant increase (p < 0. 0 5) in the concentrations of TC, TAG, LDL, VLDL & significant decrease (p < 0.0 5) in the concentrations of HDL in processed group (G2).

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Keywords

Cholesterol, histology, physiology, heart, aorta.

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