Role of Agropyron Repens Extract in Treatment Renal Calculus in Pediatric Group Alosy Baha D. Moohy1,*, Thakir Emad Maaroof2, Khalaf Shihab Ahmed3 1Professor. FIBMS-Ped, DCH, Departments of Pediatrics, College of Medicine. University of Tikrit, Iraq 2FIPMS-Ped, DCH, Departments of Pediatrics, College of Medicine. University of Tikrit, Iraq 3FIPMS-Ped, Departments of Pediatrics, College of Medicine. University of Tikrit, Iraq *Corresponding author: Baha D. Moohy Alosy: Professor. FIBMS-Ped, DCH, Departments of Pediatrics, College of Medicine. University of Tikrit, Iraq. Baba.1965@tu.edu.iq
Online published on 17 July, 2019. Abstract Background Renal, urologic, endocrine, and metabolic disorders can lead to the progress of crystallized substance in the urinary system. Infected stones may produce renal colic, hematuria and sepsis. Agropyron repens has pharmacological action as soothing mild diuretic, demulcent, antimicrobial, antioxidant objective a prospective randomized controlled study the efficacy of Agropyron repens in decrement number and size of renal calculus and its clinical feature in pediatric group. Patients and Method 50 Child between 5 to 14 years old suffering renal calculus from 3 September 2017 to 24 march 2019 in the salahaldeen hospital and personal doctor's office, 25 case as Agropyron group and 25 case as control group. Agropyron repens extract (capsule) 5 mg/kg as single dose every other day for 60 days dissolved in water while control group given supportive treatment. Guide by sequential ultrasonic urinary examination every 14 days liver function with renal function and hematological study were done and evaluated for any abnormality and/or side effect. Results Agropyron repens group were demonstrate significantly decline in number and size of stones 22 (88%)± 2.12 (P= 0.001), 23 (92%)±1.031 (P=0.003) more than control group 2 (8%)±1.02 (P = 0.12), 4 (16%)±1. 41 (P = 0.11) respectively and Agropyron group was illustrating mean±SD significantly reduction in renal colic was (77.6%) %) (19. 4 ± 1.72) which was more than in control group (16%) (4. 1 ±1.02) (P= 0.003).The mean±SD significantly higher reduction in hematuria of Agropyron group (85.96%) (21.49±1.03) which was more than in control group (24.16%) (6.04±1.06) (P= 0.002). The mean±SD reduction in Sepsis of Agropyron group (88.8%) (22.2 ±1.9) which was more than in control group (12.8%) (3.2± 1.02) mg/dL (P = 0.001). Conclusions This study indicates importance of Agropyron repens in decrement number and size of renal calculus and diminishes of renal colic, hematuria and sepsis without any side effect in pediatric group Top Keywords Renal calculus, Agropyron repens extract, pediatric group, hematuria. Top |